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Scientists found that loss of the ADA gene directly contributes to B cell tolerance problems and that these defects are mostly corrected after gene therapy.
Dr. Eric Meffre and colleagues found that loss of the ADA gene directly contributes to B cell tolerance problems and that these defects are mostly corrected after gene therapy.
Severe combined immunodeficiency is defect in the immune system that results in a loss of the adaptive immune cells known as B cells and T cells. Mutations in several different genes can lead to the development of severe combined immunodeficiency, including mutation of the adenosine deaminase (ADA) gene. Traditional treatment options, such as enzyme replacement therapy, are of limited efficacy ...
RetroSense Therapeutics, a gene therapy company dedicated to vision restoration, announced completion of a pre-IND meeting with the Center for Biological Evaluation and Research (C
RetroSense Therapeutics , a gene therapy company dedicated to vision restoration, announced completion of a pre-IND meeting with the Center for Biological Evaluation and Research (CBER) division of the FDA that took place on May 22nd 2012 regarding RetroSense’s lead biologic, RST-001 for vision restoration in retinal degenerative conditions.
TRADITION — Three former Treasure Coast high school students have been awarded the first $3,000 internships at the Vaccine and Gene Therapy Institute's research laboratories in the Tradition Center for Innovation.
Gene therapy has been used to increase the lifespan of mice by up to 24 percent - and improve their health at the same time. read more
( Massachusetts Eye and Ear Infirmary ) Forum will unite researchers, retinal specialists, companies interested in gene therapy, regulators, and the National Institutes of Healths (NIH) National Eye Institute (NEI), to examine the clinical path of optogenetic approaches in treating vision-robbing diseases such as macular degeneration, retinitis pigmentosa, and related conditions that affect more ...
Washington, May 15 (ANI): Scientists have successfully extended the lifespan of mice using gene therapy, a strategy never before employed to combat ageing.
Using gene transfer techniques pioneered by University of Florida faculty, Taiwanese doctors have restored some movement in four children bedridden with a rare, life-threatening neurological disease.
Delivering a missing enzyme to the brains of paralyzed children with a rare, life-threatening neurological disease restores movement and builds muscle mass.
Grond writes "ScienceDaily reports, 'Researchers at the Spanish National Cancer Research Centre have demonstrated that the mouse lifespan can be extended by the application in adult life of a single treatment acting directly on the animal's genes. Mice treated at the age of one lived longer by 24% on average (PDF), and those treated at the age of two, by 13%. The therapy, furthermore, produced ...
Researchers in Spain may have discovered the secret to a longer life, a new study says.
( San Diego Biotechnology Connection ) Researchers at Emory University used a standard balloon angioplasty catheter to induced transient ischemia, which when coupled with the vasodilator nitroglycerin, boosts the cell transfection of an adenovector gene construct into heart cells.
ALACHUA, Fla.--(BUSINESS WIRE)--Florida Biologix provided cGMP manufacturing for the National Taiwan University Hospital's novel gene therapy for a Phase I clinical trial. Results of the AADC trial were published May 16.
Taiwanese doctors have restored some movement in four children bedridden with a rare, life-threatening neurological disease using gene transfer. The first-in-humans achievement may also be helpful for more common diseases such as Parkinson's.